Posts Tagged ‘health


HIV-Infected Postmenopausal Women at High Risk for Bone Fractures

“As HIV-infected individuals live longer with potent antiretroviral therapy (ART), metabolic complications such as low bone density and osteoporosis are increasingly recognized,” said Michael Yin, MD of Columbia University Medical Center in New York and lead author of the study. “Although numbers of HIV-infected postmenopausal women are increasing and postmenopausal women are at highest risk for osteoporotic fractures, few studies have evaluated skeletal status in this group. We hypothesized that postmenopausal women might be particularly vulnerable to the adverse effects of HIV infection or ART on the skeleton and our results indicate that this may indeed be the case.”

To test their hypothesis, Yin and his colleagues initiated a longitudinal study to assess bone health in 92 HIV-positive and 95 HIV-negative postmenopausal women. Bone mineral density of the lumbar spine, femoral neck and hip as well as body composition were measured by dual x-ray absorptiometry (DXA). Researchers found that HIV-positive postmenopausal women had lower bone mineral density at both the spine and hip than HIV-negative postmenopausal women.

“HIV infection was independently associated with lower bone mineral density after adjusting for body mass index (BMI) and traditional osteoporosis risk factors,” said Yin. “While the reason for HIV-associated bone loss remains unclear, it may be related to increased levels of cytokines (proteins produced by cells that aid communication between cells), direct effects of antiretrovirals on bone cells or hormonal/nutritional deficiencies that are common in HIV.”

“Estrogen protects against the effect of cytokines on bone resorption,” said Yin. “Therefore, as HIV-positive women become estrogen deficient during menopause, they may be at higher risk for accelerated bone loss and fracture.”

Other researchers working on the study include Don McMahon, Chiyuan Zhang, Aimee Shu, Ronald Staron, Ivelisse Colon, Jay Dobkin, Scott Hammer and Elizabeth Shane of Columbia University Medical Center in New York, N.Y.; David Ferris of Bronx-Lebanon Hospital Center in N.Y.; and Jeffrey Laurence of Weill Cornell Medical College in New York, N.Y.

The article, “Low bone mass and high bone turnover in postmenopausal HIV-infected women,” will appear in the February 2010 issue of JCEM.


‘With Liberty And Travel For All’; Obama Lifts HIV Travel Ban


More information on the lifted travel ban:

‘With Liberty And Travel For All’; Obama Lifts HIV Travel Ban

November 2, 2009 at 10:34 AM | by JetSetCD | 0 Comments

Although the travel health focus right now is on the Swine Flu, it’s nonetheless important to remember that Swine Flu isn’t the end-all, be-all of dangerous diseases right now. After all, millions of people in the world don’t have it, unlike HIV and AIDS. Up until this weekend, those with HIV were banned from traveling to the United States due to an archaic law which was just lifted by Obama in response to a UNAIDS request for all countries to end such discriminatory travel bans: “Placing travel restrictions on people living with HIV has no public health justification. It is also a violation of human rights,” said UNAIDS executive director Michel Sidibe.

Although the ban won’t be fully lifted until next year, those who have HIV and haven’t been able to visit the US and make their dreams come true of going to Graceland and eating a slice of New York pizza now can start booking their flights.

The HIV travel ban was passed way back in 1987, when the public was very afraid of and confused about the human immunodeficiency virus (HIV) and misinformation ran rampant. These days, people have returned to not freaking out about sharing water fountains and not giving wide berths to anyone wearing a red ribbon, so it’s about time that all can travel as equals, even in first class.

For a list of seven diseased you really ought to be afraid of during travel, checking out this article at The Olympian.

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